org.biopax.paxtools.model.level2

Interface catalysis

All Superinterfaces:

BioPAXElement, Cloneable, control, entity, interaction, InteractionParticipant, Level2Element, pathwayComponent, physicalInteraction, process, Serializable, XReferrable

public interface catalysis
extends control

A control interaction in which a physical entity (a catalyst) increases the rate of a conversion interaction by lowering its activation energy. Instances of this class describe a pairing between a catalyzing entity and a catalyzed conversion. Comment: A separate catalysis instance should be created for each different conversion that a physicalEntity may catalyze and for each different physicalEntity that may catalyze a conversion. For example, a bifunctional enzyme that catalyzes two different biochemical reactions would be linked to each of those biochemical reactions by two separate instances of the catalysis class. Also, catalysis reactions from multiple different organisms could be linked to the same generic biochemical reaction (a biochemical reaction is generic if it only includes small molecules). Generally, the enzyme catalyzing a conversion is known and the use of this class is obvious. In the cases where a catalyzed reaction is known to occur but the enzyme is not known, a catalysis instance should be created without a controller specified (i.e. the CONTROLLER property should remain empty). Synonyms: facilitation, acceleration. Examples: The catalysis of a biochemical reaction by an enzyme, the enabling of a transport interaction by a membrane pore complex, and the facilitation of a complex assembly by a scaffold protein. Hexokinase -> (The "Glucose + ATP -> Glucose-6-phosphate +ADP" reaction). A plasma membrane Na+/K+ ATPase is an active transporter (antiport pump) using the energy of ATP to pump Na+ out of the cell and K+ in. Na+ from cytoplasm to extracellular space would be described in a transport instance. K+ from extracellular space to cytoplasm would be described in a transport instance. The ATPase pump would be stored in a catalysis instance controlling each of the above transport instances. A biochemical reaction that does not occur by itself under physiological conditions, but has been observed to occur in the presence of cell extract, likely via one or more unknown enzymes present in the extract, would be stored in the CONTROLLED property, with the CONTROLLER property empty.

Field Summary

Fields inherited from interface org.biopax.paxtools.model.BioPAXElement

UNKNOWN_DOUBLE, UNKNOWN_FLOAT, UNKNOWN_INT

Method Summary

Modifier and Type	Method and Description
void	addCOFACTOR(physicalEntityParticipant COFACTOR)
Set<physicalEntityParticipant>	getCOFACTOR()
Direction	getDIRECTION()
void	removeCOFACTOR(physicalEntityParticipant COFACTOR)
void	setCOFACTOR(Set<physicalEntityParticipant> COFACTOR)
void	setDIRECTION(Direction DIRECTION)

Methods inherited from interface org.biopax.paxtools.model.level2.control

addCONTROLLED, addCONTROLLER, getCONTROL_TYPE, getCONTROLLED, getCONTROLLER, removeCONTROLLED, removeCONTROLLER, setCONTROL_TYPE, setCONTROLLED, setCONTROLLER

Methods inherited from interface org.biopax.paxtools.model.level2.physicalInteraction

addINTERACTION_TYPE, getINTERACTION_TYPE, removeINTERACTION_TYPE, setINTERACTION_TYPE

Methods inherited from interface org.biopax.paxtools.model.level2.interaction

addPARTICIPANTS, getPARTICIPANTS, removePARTICIPANTS, setPARTICIPANTS

Methods inherited from interface org.biopax.paxtools.model.level2.process

addEVIDENCE, getEVIDENCE, isCONTROLLEDOf, isPATHWAY_COMPONENTSof, isSTEP_INTERACTIONSOf, removeEVIDENCE, setEVIDENCE

Methods inherited from interface org.biopax.paxtools.model.level2.entity

addAVAILABILITY, addDATA_SOURCE, addSYNONYMS, getAVAILABILITY, getDATA_SOURCE, getNAME, getSHORT_NAME, getSYNONYMS, removeAVAILABILITY, removeDATA_SOURCE, removeSYNONYMS, setAVAILABILITY, setDATA_SOURCE, setNAME, setSHORT_NAME, setSYNONYMS

Methods inherited from interface org.biopax.paxtools.model.level2.XReferrable

addXREF, findCommonPublications, findCommonRelationships, findCommonUnifications, getXREF, removeXREF, setXREF

Methods inherited from interface org.biopax.paxtools.model.level2.InteractionParticipant

isPARTICIPANTSof

Methods inherited from interface org.biopax.paxtools.model.level2.Level2Element

addCOMMENT, getCOMMENT, removeCOMMENT, setCOMMENT

Methods inherited from interface org.biopax.paxtools.model.BioPAXElement

equivalenceCode, getAnnotations, getModelInterface, getUri, isEquivalent

Method Detail

addCOFACTOR

void addCOFACTOR(physicalEntityParticipant COFACTOR)

removeCOFACTOR

void removeCOFACTOR(physicalEntityParticipant COFACTOR)

setCOFACTOR

void setCOFACTOR(Set<physicalEntityParticipant> COFACTOR)

getCOFACTOR

Set<physicalEntityParticipant> getCOFACTOR()

getDIRECTION

Direction getDIRECTION()

setDIRECTION

void setDIRECTION(Direction DIRECTION)